I wonder what the implications for transplant recipients are.
this post was submitted on 16 Sep 2023
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"an inverse vaccine"
Oh good, at least they didn't choose a name that's gonna cause confusion.
TIL you can wait until you have the disease to take the vaccine. So if my kid gets polio, I'll give them the vaccine then, but I don't want to risk anything bad happening so I'll wait. I'm glad I did my research.
That naming does makes sense, given what the treatment does, although I agree they really need to work on their marketing and come up with a term that won't cause confusion or get the anti-vax folk excitable.
From the article:
"A typical vaccine teaches the human immune system to recognize a virus or bacteria as an enemy that should be attacked. The new “inverse vaccine” does just the opposite: it removes the immune system’s memory of one molecule. While such immune memory erasure would be unwanted for infectious diseases, it can stop autoimmune reactions like those seen in multiple sclerosis, type I diabetes, rheumatoid arthritis, or Crohn’s disease, in which the immune system attacks a person’s healthy tissues."
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"Inverse vaccine" sounds like instead of preventing a disease through a weakened or dead version of the thing you're preventing, they inject you with a stronger version of the thing you already have to kick it's ass.
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As someone with Celiac disease with a women who also is celiac, this gives so much hope of living a normal life again.
Please happen !
... initial phase I safety trials have already been carried out in people with celiac disease ...
In case you happened to miss that part. Good luck!
Notably they trialled first for coeliac autoimmune, but it'll be 2024 before phase 2 results are out for that. About 10 years back there was a similar vaccine which also passed phase 1 trials but failed at phase 2. Phase 1 is basically testing that the vaccine does no harm in small groups and it is phase 2 where they measure if it is actually efficacious and to what level. If it passes phase 2, then get your hopes up.
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