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Almost ALL drug research is based on what is called fundamental research, which is basic research that at first glance does not seem to lead to any practical application. E.g., one group might discover an unusual protein side chain, another group then found that this side chain is inhibited by a certain molecule and another traced the metabolic pathway. These are usually done by postgrad students at universities all around the world and funded by their own governments via research grants. Almost always, these grants are paid by the country's tax payers.
Here's the kicker. To get noticed and to get promotions, these researchers have to PAY publishing companies to publish their findings in journals, after which the publisher owns the copyright to it and put up an obscene paywall.
Then, pharmaceutical companies skim these publications, usually combining the findings of 100s of articles as their starting point to develop new drugs. E.g. that protein side chain mentioned earlier turned out to be a target for anticancer drugs. Without these basic findings, big pharma don't even know where to start. Essentially, governments and tax payers around the world subsidize the basic research of big pharma only for these companies to charge obscene prices and region lock the drugs.