CPU brand (as in AMD/Intel) makes little if any difference in linux, stark contrast to Nvidia/AMD GPU. There was a period of time where some of the intel CPU "efficiency cores" were not properly scheduled in the kernel but I think that's a lot better now as long as you use a relatively new kernel. There are different power/frequency management flags you can pass to the boot params based on intel/amd but that probably makes more of a difference if you're on battery: https://wiki.archlinux.org/title/Ryzen
I think there used to be some limitation in using resizeable BAR with an intel CPU and AMD GPU, but that hasn't been an issue for a while.
I have a 5950x with a 6900xt in my linux box and have had no complaints.