You're using flatpak, right? Flatpak uses "portals" to provide access to other parts of your system. When you open files in flatpak apps, you'll see this folder used for those.
These shouldn't actually take up any meaningful space, and I wouldn't delete anything unless you're experiencing an issue.
I'm running kde6 on fedora rawhide kinoite, it's pretty stable.
Minor point of clarification though, kinoite isn't immutable ootb, it's atomic (which is to say it either fully updates or doesn't. Immutable is an experimental setting you can enable though)