I should have used the preview ^_^
PS: Again!
I should have used the preview ^_^
PS: Again!
Reading about the hubris of young Yud is a bit sad, a proper Tragedy. Then I have to remind myself that he remains a manipulator, and that he should be old enough to stop believe—and promote—in magical thinking.
More tedious work with worse pay \o/
Also a subjectively bad one at that—given his america-brained position on wanting to maintain a single executive not that suprising but:
Haven't read the whole thing but I do chuckle at this part from the synopsis of the white paper:
[...] Our results suggest that AlphaProteo can generate binders "ready-to-use" for many research applications using only one round of medium-throughput screening and no further optimization.
And a corresponding anti-sneer from Yud (xcancel.com):
@ESYudkowsky: DeepMind just published AlphaProteo for de novo design of binding proteins. As a reminder, I called this in 2004. And fools said, and still said quite recently, that DM's reported oneshot designs would be impossible even to a superintelligence without many testing iterations.
Now medium-throughput is not a commonly defined term, but it's what DeepMind seems to call 96-well testing, which wikipedia just calls the smallest size of high-throughput screening—but I guess that sounds less impressive in a synopsis.
Which as I understand it basically boils down to "Hundreds of tests! But Once!".
Does 100 count as one or many iterations?
Also was all of this not guided by the researchers and not from-first-principles-analyzing-only-3-frames-of-the-video-of-a-falling-apple-and-deducing-the-whole-of-physics path so espoused by Yud?
Also does the paper not claim success for 7 proteins and failure for 1, making it maybe a tad early for claiming I-told-you-so?
Also real-life-complexity-of-myriads-and-myriads-of-protein-and-unforeseen-interactions?
Another dumb take from Yud on twitter (xcancel.com):
@ESYudkowsky: The worst common electoral system after First Past The Post - possibly even a worse one - is the parliamentary republic, with its absurd alliances and frequently falling governments.
A possible amendment is to require 60% approval to replace a Chief Executive; who otherwise serves indefinitely, and appoints their own successor if no 60% majority can be scraped together. The parliament's main job would be legislation, not seizing the spoils of the executive branch of government on a regular basis.
Anything like this ever been tried historically? (ChatGPT was incapable of understanding the question.)
BasicSteps™ for making cake:
Any further details are self-evident really.
Quinn enters the dark and cold forest, crossing the threshold, an omnipresent sense of foreboding permeates the air, before being killed by a grue.
And also closing with:
To tie the bow nicely.